TABLE 1.
Putative T-cell antigens of Francisella tularensis subsp. novicida containing potential HLA-DR4 binding peptides
| ORFa in U112 | Fraction identified | Protein function | Accession no. | Molecular mass (kDa) | ORF in SCHU S4 (% identity) |
|---|---|---|---|---|---|
| FTN_0119 | 5.10 | Conserved outer membrane protein | YP_897784 | 19.4 | FTT_1747 (100) |
| FTN_0218 | 5.8 | Dihydropteridine reductase | YP_897882 | 24.8 | FTT_0304 (99.08) |
| FTN_0320 | 5.9 | Hypothetical protein | YP_897980 | 29.3 | FTT_1589 (97.98) |
| FTN_0545 | 5.10 | Glycosyltransferase, group 2 family protein | YP_898194 | 36.1 | FTT_0454 (100) |
| FTN_0597 | 5.9 | Protein disulfide isomerase | YP_898246 | 27.9 | FTT_0507 (98.43) |
| FTN_0918 | 5.9 | Conserved hypothetical lipoprotein | YP_898560 | 23.5 | FTT_1040 (97.54) |
| FTN_1220 | 6.5 | Sugar transferase involved in lipopolysaccharide synthesis | YP_898855 | 52.9 | FTT_0790 (98.06) |
| FTN_1381 | 7.3 | Hypothetical protein | YP_899005 | 53.3 | FTT_1415 (100) |
a
ORF, open reading frame.