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Percent Kinase Target Inhibition of Dasatinib Over Time
| Time on Dasatinib (months) | No. of Evaluable Patients | Detectable p-CrkL-Tyr207 |
Detectable pABL-Tyr245 |
||
|---|---|---|---|---|---|
| No. of Patients | % | No. of Patients | % | ||
| 1 | 38 | 36 | 94.7 | 30 | 78.9 |
| 3 | 36 | 7 | 19.4 | 6 | 16.7 |
| 6 | 38 | 4 | 10.5 | 3 | 7.9 |
| 12 | 32 | 2 | 6.2 | 1 | 3.1 |
| 18 | 23 | 3 | 13.0 | 2 | 8.7 |
