Table 3.
Toxicity | Toxicity by Grade |
|||||||
---|---|---|---|---|---|---|---|---|
1-2 |
3 |
4 |
All |
|||||
No. | % | No. | % | No. | % | No. | % | |
Hematologic/infections | ||||||||
Leukopenia | 7 | 18 | 13 | 34 | 13 | 34 | 33 | 87 |
Neutropenia | 8 | 21 | 9 | 24 | 16 | 42 | 33 | 87 |
Anemia | 23 | 61 | 10 | 26 | — | — | 33 | 87 |
Thrombocytopenia | 17 | 45 | 4 | 11 | 2 | 5 | 23 | 61 |
Documented infections | 5 | 13 | 10 | 26 | — | — | 15 | 39 |
Febrile neutropenia | — | — | 5 | 13 | — | — | 5 | 13 |
Nonhematologic | ||||||||
Fatigue | 30 | 79 | 5 | 13 | — | — | 35 | 92 |
Nausea | 27 | 71 | 3 | 8 | — | — | 30 | 79 |
Vomiting | 20 | 53 | 3 | 8 | — | — | 23 | 61 |
Diarrhea | 18 | 47 | 9 | 24 | — | — | 27 | 71 |
Anorexia | 23 | 61 | 1 | 3 | — | — | 24 | 63 |
Hypocalcemia | 17 | 45 | 2 | 5 | — | — | 19 | 50 |
Tumor lysis syndrome | — | — | 5 | 13 | — | — | 5 | 13 |