Table 1.

Copula R² Values and Corresponding 95% CIs

Factor	5-Year Median OS		6-Year Median OS		7-Year Median OS
	R2	95% CI	R2	95% CI	R2	95% CI
Association with 3-year DFS (median)
Actual data	0.75	0.55 to 0.95	0.78	0.60 to 0.96	0.82	0.67 to 0.97
Double TRD	0.51	0.18 to 0.83	0.67	0.42 to 0.92	0.70	0.48 to 0.93
Recurrence dependent	0.54	0.23 to 0.85	0.64	0.37 to 0.91	0.76	0.56 to 0.95
Stage dependent	0.44	0.10 to 0.78	0.61	0.32 to 0.89	0.68	0.43 to 0.92
Treatment dependent (surgery only v chemotherapy)	0.29	0.0 to 0.64	0.41	0.06 to 0.76	0.49	0.16 to 0.82
Association with 2-year DFS (median)
Actual data	0.73	0.51 to 0.94	0.77	0.58 to 0.96	0.80	0.63 to 0.96
Double TRD	0.51	0.18 to 0.83	0.67	0.41 to 0.92	0.70	0.46 to 0.93

Abbreviations: OS, overall survival; DFS, disease-free survival; TRD, time from recurrence to death.