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. 2009 Nov 23;28(2):279–284. doi: 10.1200/JCO.2009.25.0274

Table 2.

Neutropenia and FcγR Polymorphisms in 24 Patients Receiving Two Courses of Rituximab

Neutropenia FcγR IIIa Polymorphism
FcγR IIa Polymorphism
V/V (n = 3) V/F (n = 9) F/F (n = 12) H/H (n = 7) H/R (n = 11) R/R (n = 6)
No neutropenia* 1 3 9 4 5 4
Neutropenia in one course 0 4 3 1 4 2
Neutropenia in both courses 2 2 0 2 2 0
Mean 1.33 0.89 0.25 0.77 0.72 0.33
Spearman rank correlation
    r 0.495 0.140
    P .014 .520
*

Grade 3 or 4 (absolute neutrophil count < 1,000/μL).