Table 2.

Adjusted odds ratios (OR) for the development of upper urinary tract cancer and bladder cancer by multivariable logistic regression models^*

	Upper UTC			Bladder cancer
Variable	n = 1985	Adjusted OR (95% CI)	P	n = 2609	Adjusted OR (95% CI)	P
Residence in township endemic for   black foot disease
No	1953	1.0 (Referent)		2553	1.0 (Referent)
Yes	32	3.8 (2.6 to 5.6)	<.001	56	5.0 (3.6 to 6.9)	<.001
Chronic UTI
No	1965	1.0 (Referent)		2546	1.0 (Referent)
Yes	20	0.9 (0.6 to 1.4)	.585	63	2.3 (1.7 to 3.0)	<.001
Mu-Tong, total amount prescribed, g
0	1698	1.0 (Referent)		2289	1.0 (Referent)
1–60	239	1.1 (0.9 to 1.3)	.244	250	1.0 (0.8 to 1.2)	.762
61–100	22	1.5 (0.9 to 2.3)	.084	28	1.7 (1.1 to 2.6)	.011
101–200	19	1.8 (1.1 to 2.9)	.026	27	2.2 (1.4 to 3.4)	<.001
> 200	7	1.3 (0.6 to 3.0)	.530	15	2.8 (1.6 to 5.1)	<.001
Fangchi, total amount prescribed, g
0	1684	1.0 (Referent)		2243	1.0 (Referent)
1–60	282	0.9 (0.8 to 1.0)	.093	341	1.0 (0.8 to 1.1)	.610
61–100	6	0.6 (0.3 to 1.4)	.250	9	0.7 (0.4 to 1.5)	.394
>100	13	1.3 (0.7 to 2.4)	.350	16	1.3 (0.8 to 2.3)	.306
Xi-Xin, total amount prescribed, g
0	1556	1.0 (Referent)		2124	1.0 (Referent)
1–100	391	1.1 (1.0 to 1.3)	.087	448	1.1 (0.96 to 1.2)	.211
101–300	27	1.0 (0.6 to 1.5)	.859	27	0.7 (0.5 to 1.1)	.173
>300	11	1.8 (0.9 to 3.5)	.099	10	0.9 (0.4 to 1.8)	.706

^*ORs adjusted for age, sex, residence in a township where black foot disease was endemic, and history of chronic UTI. CI = confidence interval; UTC = urinary tract cancer; UTI = urinary tract infection.