Table 2. Baseline characteristics of patients in the Virahep-C viral genetics cohort.
Feature | Statistic | SVRa | NRb | P valuec |
Number of patients | N | 48 | 46 | – |
AAd | N (%) | 21 (43.8%) | 26 (56.5%) | 0.2207 |
Male | N (%) | 31 (64.6%) | 37 (80.4%) | 0.0640 |
Genotype 1a | N (%) | 22 (45.8%) | 25 (54.3%) | 0.5606 |
Age (years) | median (25th, 75th) | 46.5 (42.0, 50.0) | 49.0 (45.0,53.0) | 0.2777 |
Body weight (kg) | median (25th, 75th) | 84.6 (72.0, 96.8) | 89.6 (79.2, 101.7) | 0.1022 |
HCV RNA (log10IU/ml) | median (25th, 75th) | 6.0 (5.4, 6.8) | 6.6 (6.4, 6.7) | 0.0006 |
ALTe (U/L) | median (25th, 75th) | 60.5 (44.0, 88.0) | 69.5 (54.0, 102.0) | 0.6145 |
Albumin (g/dl) | median (25th, 75th) | 4.2 (4.0, 4.4) | 4.2 (4.0, 4.4) | 0.8317 |
Platelets (×1,000/mm) | median (25th, 75th) | 249.0 (197.5, 296.0) | 205.5 (173.0, 250.0) | 0.0006 |
AFPf (ng/ml) | median (25th, 75th) | 4.1 (2.6, 5.6) | 5.6 (3.7, 11.6) | 0.7657 |
Ishak necroinflamatory score (0–18) | median (25th, 75th) | 7.0 (5.0, 9.0) | 7.5 (6.0, 9.0) | 0.1109 |
Ishak fibrosis score (0–6) | median (25th, 75th) | 2.0 (1.0, 3.0) | 2.0 (1.0, 3.0) | 0.2561 |
Sustained viral response.
Non-response.
Univariate Poisson regression model.
African American.
Alanine aminotransferase in serum.
Alpha fetal protein in serum.