Table 4. Genetic associations in combined MoBa and Cenn samples.

Sample	Gene	SNP	Allele	Cenn Case Allele Freq	Cenn Cont Allele Freq	Cenn Allele p	Cenn Genotype p	MoBa Case Allele Freq	MoBa Cont Allele Freq	MoBa Allele p	MoBa Genotype p	Pooled Case Allele Freq	Pooled Cont Allele Freq	Pooled Allele p	Pooled Genotype p
Maternal	PTGER3	rs977214	G	0.09	0.13	0.17	5×10−3	0.06	0.09	0.06	0.04	0.071	0.112	0.02*	3×10−4 **
		rs6665776	A	0.09	0.12	0.24	0.01	0.06	0.09	0.06	0.04	0.071	0.11	0.02*	5×10−4 *
		rs2072947	C	0.53	0.44	0.02	0.03	0.41	0.46	0.21	0.03	0.46	0.45	0.58*	0.04*
Fetal	PON1	rs854552	C	0.22	0.28	0.12	0.25	0.21	0.30	2×10−3	6×10−3	0.21	0.29	8×10−4 *	2×10−3 *
		rs2272365	G	0.19	0.13	0.05	0.05	0.17	0.12	0.04	0.12	0.18	0.13	5×10−3 *	0.01*

¹cases deviated from HWE at rs977214 (p = 0.02), rs6665776 (p = 0.02).

²controls deviated from HWE at rs977214 (p = 0.05).

*Significant after correction for multiple testing with FDR (q = 0.2).

**Significant after correction for multiple testing with Bonferroni.