Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2009 Aug;15(8):1214–1221. doi: 10.3201/eid1508.081218

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.

PMC Copyright notice

Lesion profiles and regional distributions of atypical proteinase K–resistant prion protein (PrP^res) in the brain of porcine PrP transgenic mice infected, either in 1st passage (white column) or in 2nd passage (black column) with cattle bovine spongiform encephalopathy (BSE) (panels A and D), sheep BSE (panels B and E), or atypical scrapie (panels C and F) agents. A–C) Lesion scoring of 9 areas of gray matter (G) and white matter (W) in mice brains: dorsal medulla (G1), cerebellar cortex (G2), superior colliculus (G3), hypothalamus (G4), medial thalamus (G5), hippocampus (G6), septum (G7), medial cerebral cortex at the level of the thalamus (G8) and at the level of the septum (G9), cerebellum (W1), mesencephalic tegmentum (W2) and pyramidal tract (W3). Error bars indicate SE. D–F) Histoblots of representative coronal sections at the level of the hippocampus.