Table 2.
Characteristics at Diagnosis of Patients With ALL Who Received at Least One Treatment for Medullary Relapse (n = 225)
| Characteristic | No. of Patients (n = 225) | % |
|---|---|---|
| Age, years | ||
| < 1 (infants) | 8 | 3.6 |
| 1-9 | 151 | 67.1 |
| ≥ 10 | 66 | 29.3 |
| WBC counts/μL | ||
| < 50,000 | 148 | 72.9 |
| ≥ 50,000 | 55 | 27.1 |
| Unknown | 22 | |
| NCI risk criteria at diagnosis | ||
| Non-infants, standard risk | 102 | 45.3 |
| Non-infants, high risk | 99 | 44.0 |
| Non-infants, unknown | 16 | 7.1 |
| Infants | 8 | 3.6 |
| Sex | ||
| Female | 93 | 41.3 |
| Male | 132 | 58.7 |
| Testis positive | ||
| Yes | 4 | 1.9 |
| No | 212 | 98.1 |
| Unknown | 9 | |
| Mediastinal mass | ||
| Yes | 7 | 3.2 |
| No | 209 | 96.8 |
| Unknown | 9 | |
| CNS disease | ||
| Yes | 18 | 8.3 |
| No | 198 | 91.7 |
| Unknown | 9 | |
| Immunophenotype | ||
| Pre B cell | 195 | 86.7 |
| T cell | 30 | 13.3 |
| Karyotype | ||
| Normal | 74 | 43.0 |
| Hypodiploidy | 8 | 4.7 |
| Hyperdiploidy | 16 | 9.3 |
| t(12;21) | 3 | 1.7 |
| t(1;19) | 8 | 4.7 |
| t(4;11) | 2 | 1.2 |
| t(9;22) | 4 | 2.3 |
| Other | 57 | 33.1 |
| Unknown | 53 |
Abbreviations: ALL, acute lymphoblastic leukemia; NCI, National Cancer Institute.