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. 2009 Dec 21;28(4):690–697. doi: 10.1200/JCO.2009.22.2257

Table 4.

New Predictors of Progression in Smoldering Multiple Myeloma

Plasma cell mass12
    M-protein concentration
    Proportion of BMPC
Free light chain immunoglobulin ratio13
Aberrant immunophenotype and immunoparesis14
    ≥ 95% BMPC with abnormal phenotype
    Decrease of one or two of the uninvolved immunoglobulins
Evolution pattern: evolving versus nonevolving9

Abbreviation: BMPC, bone marrow plasma cells.