Table 4.
New Predictors of Progression in Smoldering Multiple Myeloma
| Plasma cell mass12 |
| M-protein concentration |
| Proportion of BMPC |
| Free light chain immunoglobulin ratio13 |
| Aberrant immunophenotype and immunoparesis14 |
| ≥ 95% BMPC with abnormal phenotype |
| Decrease of one or two of the uninvolved immunoglobulins |
| Evolution pattern: evolving versus nonevolving9 |
Abbreviation: BMPC, bone marrow plasma cells.