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. 2010 Jan 12;123(3):472–483. doi: 10.1242/jcs.048074

Fig. 6.

Fig. 6.

Adherens junctions are aberrant in nestin-Vangl2 embryos. (A-H) Actin distribution over wild-type and nestin-Vangl2 embryos of the indicated ages. Wild-type embryos display clear actin enrichment over the adherens junctions (arrows in A,B,E,F). High magnification reveals ring-shaped adherens junctions (arrows in B,F). Nestin-Vangl2 embryos display stretches without actin enrichment (arrows in C,D,G) and patches of actin (arrowheads in D,H). (I-P) Distribution of β-catenin and N-cadherin correlates with the actin distribution, with clear enrichment over the adherens junctions in wild-type embryos (I,J,M,N), and no enrichment and a patchy distribution in the nestin-Vangl2 embryos (K,L,O,P). B,F,J,N and D,H,L,P are enlarged sections from A,E,I,M and C,G,K,O, respectively. Scale bars: 50 μm.