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. 2010 Feb 4;5(2):e9045. doi: 10.1371/journal.pone.0009045

Table 1. 5-FOA-resistant uracil auxotrophs of H. salinarum NRC-1 with mutations in multiple UMP biosynthetic genes.

Mutations(1)
Genes analyzed # of clones sequenced pyrF pyrE2 none
pyrF 4 2 1 1
pyrE1
pyrE2
pyrF 19 5 nd 14
pyrE1
pyrF 16 1(2) 15 1
pyrE2
pyrE1 8 nd 4 4
pyrE2
(1)

no mutation in pyrE1.

(2)

mutation in both pyrF and pyrE2.

nd not determined.