Table 2. Types and positions of spontaneous mutations in the pyrF and pyrE2 genes.
Gene position (bp) | Number of independent isolates with this mutation | Type of mutation(1) |
pyrF | ||
354 | 4 | Insertion (C) |
356 | 4 | Insertion (C) |
357 | 4 | Insertion (A) |
359 | 4 | Insertion (CG) |
360 | 1 | Insertion (A) |
361 | 4 | G→C(2) |
362 | 4 | Insertion (TC) |
365 | 4 | Insertion (G) |
397 | 8 | G→T(2) |
463 | 1 | C→A(2) |
798 | 3 | Insertion (C) |
pyrE2 | ||
382 | 42 | Deletion (GTCGACG) |
390 | 42 | C→T |
392 | 42 | Deletion (T) |
394 | 42 | C→G(2) |
397 | 42 | Deletion (G) |
insertion indicated was found prior to the stated base pair position.
non-synonymous base pair changes.