Figure 8. Summary of over-represented gene categories.

Several functional categories, based on PANTHER annotations and GSEA results, are significantly perturbed upon loss of α9 nicotinic subunit at postnatal time periods P13 and P60. While several processes are common to both ages (orange box), others are preferentially expressed at P13 (green box) or P60 (blue box). Only Wnt/β-catenin pathway (highlighted in red) is identified as over-represented in α9^−/− by both PANTHER and GSEA analyses.