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Biodistribution of 89Zr-Df-Bz-NCS-cetuximab (black bars) and 89Zr-N-sucDf-cetuximab (white bars) in A431 tumor-bearing nude mice at 24 h (a), 48 h (b), 72 h (c), and 120 h (d) after injection. Total administered mAb dose: 500 μg. Mean (%ID/g) ± SD at each time point after injection (n = 4 animals per time point for each conjugate). Significant differences (P < 0.01) in biodistribution between both radioimmunoconjugates are marked with an asterisk
