Table 2.
Immunoglobulin G reactivity against various secretory antigens of M. tuberculosis at cut off decided by ROC analysis
| Antigen | Cutoff | Sensitivity (%) | Specificity (%) | +PV (%) | −PV (%) | +LR | −LR | ROC area |
|---|---|---|---|---|---|---|---|---|
| ESAT-6 | 0.331 | 64.9 | 88.9 | 95.3 | 42.1 | 5.84 | 0.39 | 0.743 |
| CFP-10 | 0.293 | 66.0 | 85.2 | 93.9 | 41.8 | 4.45 | 0.40 | 0.746 |
| Ag85 complex | 0.150 | 84.1 | 85.2 | 95.2 | 60.5 | 5.67 | 0.19 | 0.879 |
| Ag85A | 0.119 | 44.6 | 55.6 | 77.4 | 23.2 | 1.01 | 0.10 | 0.496 |
| Ag85B | 0.163 | 34.0 | 74.1 | 82.8 | 24.4 | 1.31 | 0.89 | 0.545 |
| Ag85C | 0.072 | 80.9 | 40.7 | 82.6 | 37.9 | 1.36 | 0.47 | 0.603 |
| Cocktail | 0.114 | 51.1 | 85.2 | 92.3 | 33.3 | 3.45 | 0.57 | 0.685 |