Table II.
Point mutation oligonucleotides used for EMSA
Binding: ++ indicates strongest binding; + indicates binding that is less strong but capable of competing with wild type for binding to rSMH1; – indicates failure to compete or no observed binding to rSMH1. The positions of the two tandem copies of wild-type telomere repeats are indicated by underline in first two sequences. The individual point mutations are indicated by gray boxes.
