Table 1.
Metabolic parameters of type 2 diabetic rats after 4 weeks of treatment.
| Groups | Dose | Serum cholesterol (mg/dL) |
Serum triglyceride (mg/dL) |
Serum urea (mg/dL) |
Serum creatinine (mg/dL) |
Hepatic glycogen (mg/100g of liver) |
| Normal control | 76.2 ±6.3 | 109.1 ± 2.3 | 52.2 ± 2.3 | 26.9 ± 1.3 | 59.2 ± 2.2 | |
| Diabetic control | 117.1 ± 6.7** | 177.5 ± 8.7** | 90.1 ± 4.8** | 48.4 ± 2.7** | 68.0 ± 2.6* | |
| Extract | 40 mg/kg | 52.7 ± 1.9*$$ | 99.0 ± 4.7$$ | 59.2 ± 2.9$$ | 30.1 ± 2.2$$ | 61.8 ± 2.5 |
| Extract | 75 mg/kg | 67.0 ± 6.1$$ | 102.7 ± 5.6$$ | 63.1 ± 7.3$ | 34.6 ± 1.4**$$ | 65.6 ± 0.8* |
| Glibenclamide | 5 mg/kg | 80.7 ± 9.2$ | 113.0 ± 3.7$$ | 65.8 ± 5.1*$ | 35.1 ± 3.0*$ | 63.4 ± 4.6 |
Values are given as mean ± SEM for five rats in each group.
*, P < 0.05; **, P < 0.01, with respect to normal control group.
$, P < 0.05; $$, P < 0.01, with respect to diabetic control group.