Table 2.
Values of inhibitory concentrations (µg/ml) of active plant species and antibiotics
| Plant species | Tested part | ATCC and hospital strains of Streptococcus pneumoniae (n = 12) | ||||||||||||||
| ATCC | Sensitive strains | Penicillin-resistant strains | ||||||||||||||
| 49619 | 24 | 615 | 624 | 1948 | 2474 | 6771 | 554 | 52 | 59 | 525 | 563 | |||||
| IC100 | IC50 | IC100m | Range of IC100 |
|||||||||||||
| Erythrina senegalensis | Roots | 6 (2) | 12(2) | 12(2) | 12(2) | 12(2) | 6(2) | 12(2) | 6(4) | 6(2) | >1500 | 3(2) | 23(4) | 12(2) | 10 | 23-3 |
| Piliostigma thonningii | Leaves (young) | 47(2) | 23(2) | 47(4) | 47(2) | 47(4) | 94(2) | 94(4) | 188 | 47(4) | 47(2) | >1500 | >1500 | 47(2) | 68,1 | 47-23 |
| Waltheria lanceolata | Roots | 188 | 47(2) | 94(4) | 188 | 47(2) | 94(4) | 47(4) | 47(4) | 47(4) | >1500 | 94(4) | 23(2) | 47(4) | 83,27 | 188-23 |
| Uapaca togoensis | Stem bark | 94(4) | 6(2) | 94(4) | 188 | 94(4) | 94(4) | 188 | 375 | 6(2) | 94(4) | >1500 | >1500 | 94(4) | 100 | 94-23 |
| Leaves | 188 | 94(4) | 94(4) | 188 | 94(4) | 188 | 188 | 188 | 94(4) | >1500 | 188 | 23(2) | 94(4) | > 100 | 188-94 | |
| Andira inermis | Leaves | 47(2) | 23(2) | 94(4) | 94(4) | 94(4) | 188 | 94(4) | 94(4) | 23(4) | >1500 | 94(4) | 94(4) | 94(4) | > 100 | 188-94 |
| Keetia hispida | Leaves | 94(2) | 94(2) | 188 | 188 | 94(4) | 188 | 188 | 94(4) | 94(4) | >1500 | 94(4) | 94(4) | 94(4) | > 100 | 188-6 |
| Garcinia afzelii | Leaves | 94(4) | 94(2) | 94(4) | 94(4) | 94(4) | 188 | 188 | 94(4) | 94(4) | 94(4) | >1500 | >1500 | > 100 | > 100 | 188-94 |
| Roots | 94(2) | 23(2) | 188 | 188 | 188 | 188 | 188 | 375 | 23(2) | 188 | >1500 | >1500 | > 100 | > 100 | 375-23 | |
| Combretum molle | Leaves | 94(4) | 6(2) | 188 | 188 | 188 | 375 | 188 | 94(4) | 6(4) | >1500 | 47(2) | 47(2) | > 100 | > 100 | 375-6 |
| Antibiotics | ||||||||||||||||
| Gentamicin | 25 | 6,25 | 6,25 | 12,5 | 25 | 1,6 | >50 | 50 | >50 | >50 | 50 | 50 | 12,5 | 15,6 | >50-1,6 | |
| Tetracycline | 1,6 | 6,25 | 3,215 | 6,25 | >50 | 6,25 | 1,6 | 50 | >50 | >50 | 50 | 50 | 6,25 | 9,2 | >50-1,6 |
Bold type : value of IC100 = 94 µg/ml or lower ; in brackets : value of BC/ IC100 ; IC100m = average
All experiments were run in triplicate.