Table 1.
Acute toxicity of hexane extract of A. occidentale administered by oral route to mice.
Dose (g/kg) | N | Toxic symptoms | Dead mice | D/T | % of mortality |
2 | 10 | None | 0 | 0/10 | 0 |
6 | 10 | None | 0 | 0/10 | 0 |
10 | 10 | Asthenia, hypoactivity | 0 | 0/10 | 0 |
14 | 10 | Asthenia, anorexia, hypoactivity | 0 | 0/10 | 0 |
18 | 10 | Asthenia, anorexia, diarrhoea, syncope | 3 | 3/10 | 30 |
22 | 10 | Asthenia, anorexia, diarrhoea, syncope | 7 | 7/10 | 70 |
26 | 10 | Asthenia, anorexia, diarrhoea, syncope | 10 | 10/10 | 100 |
Total | 80 | 20 | 20/70 | 28,57 |