Table 4.

Biochemical parameters relating to blood of mice (control and groups I-III) after daily administration of 0, 6 10 and 14 g/kg of hexane extract of A. occidentale for 56 days.

Parameter	Control group	Group I	Group II	Group III
ASAT (U/L)	51,3±0,2	42,5±0,1	37,7±0,2	29,3±0,2**
ALAT (U/L)	45,0±0,2	38,3±0,1	35,3±0,2	28,4±0,2*
Creatinine (mmol/L)	15,5±0,2	21,0±0,1	26,6±0,3	45,0±0,1**
Urea (mmol/L)	35,5±0,1	32,5±0,1	44,0±0,2	49±0,3**
Total protein (g/L)	45,5±0,2	44,0±0,1	32,0±0,2	28±0,2**

The hexane extract of A. occidentale was given daily by oral route to groups of mice (n=10) at the doses: I (6g/kg), II (10 g/kg) and III (14 g/kg) for 56 days. Biochemical parameters were measured after the last day of treatment. The data are expressed as mean ±S.E.M. Significances differences for each group at each time period vs control values: *P<0.05; *P<0.01.