Table 3.

Effect of administration of aqueous stem bark extract of Stereospermum kunthianum on pentylenetetrazole - induced seizures in mice

	Onset of	Onset of tonic	Time of death	Qauntal	Survival
Treatment	clonic	seizures(min)	(min)	death	(%)
	seizures(min)
Normal saline	1.65±0.12	4.44±0.49	8.58±0.74	7/7	0.00
(10ml/kg,i.p.)
S. kunthianum	2.38±0.23*	5.50±0.65	10.0±0.78	7/7	0.00
(100mg/kg,i.p.)
S. kunthianum	2.75±0.25*	5.79±0.48	11.50±0.61	7/7	0.00
(200mg/kg,i.p.)
S. kunthianum	3.0±0.20*	6.33±0.33*	12.0±0.80	5/7	28.6
(400mg/kg, i.p.)
Ethosuximide	4.67±1.05*	10.0±00*	23.0±0.71*	3/7	57.1
(150mg/kg,sc.)

Values are mean ±SEM, *P<0.05, significantly different from the distilled water treated animals, Student t - test (n=7)