Table 3.
MIC, MBC and IC50 values (µ g/ml) of Holarrhena floribunda extracts in the macrodilution assays compared to chloramphenicol.
Crude extract | Total alkaloid fraction | chloramphenicol | ||||||||||
Inhibition parameters Bacterial strains |
MIC | MBC | IC50 | MIC | MBC | IC50 | MIC | MBC | IC50 | |||
B. cereus | 215 | 390 | 110 | 1.8 | 150 | 280 | 70 | 1.8 | 18.5 | 33 | 9.5 | 1.8 |
B. subtilis | 185 | 320 | 100 | 1.7 | 95 | 170 | 45 | 1.8 | 9 | 16 | 4.5 | 1.8 |
B. megaterium | 175 | 317 | 90 | 1.8 | 90 | 160 | 40 | 1.8 | 36 | 70.5 | 18 | 1.9 |
B. stearother mophilus |
115 | 210 | 55 | 1.8 | 50 | 105 | 30 | 2 | 8.5 | 14.5 | 4.5 | 1.7 |