Table 3.
Treatment groups (n=5) |
Dose (mg/kg) |
Oedema diameter(cm) | ||||
1 hour | 2 hours | 3 hours | 4 hours | 5 hours | ||
Normal Saline | 10ml/kg | 0.706± 0.66 | 0.81± 0.60 | 0.822± 0.57 | 0836± 0.48 | 0.882± 0.19 |
Diclofenac | 20 | 0.594±0.23a | 0.594±0.11c | 0.61± 0.08 c | 0.618±0.31c | 0.598± 0.10c |
O. gratissimum | 50 | 0.532±0.13a | 0.498± 0.47c | 0.502±0.29c | 0.49± 0.18 c | 0.444± 0.19c |
O. gratissimum | 100 | 0.450± 0.68b | 0.462±0.17 c | 0.434±0.09 c | 0.442± 0.20 c | 0.414± 0.09c |
O. gratissimum | 200 | 0.556±0.07 a | 0.452± 0.16c | 0.386±0.24c | 0.386± 0.24 c | 0.400 0.374c |
p<0.001 | p<0.001 | p<0.01 | p<0.001 | p<0.001 | ||
One way ANOVA | F=4.502 | F= 17.014 | F= 30.798 | F= 35.929 | F= 89.528 |
Each value is mean ±SEM of 5 rats. ap<0.05; bp<0.01; cp<0.001 compared to control. NS: statistically not significant