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. 2008 Jan 22;5(2):141–146. doi: 10.4314/ajtcam.v5i2.31265

Table 3.

Effect of aqueous leaves extract of Ocimum gratissimum on formalin -induced paw Oedema in rats

Treatment
groups
(n=5)
Dose
(mg/kg)
Oedema diameter(cm)

1 hour 2 hours 3 hours 4 hours 5 hours
Normal Saline 10ml/kg 0.706± 0.66 0.81± 0.60 0.822± 0.57 0836± 0.48 0.882± 0.19
Diclofenac 20 0.594±0.23a 0.594±0.11c 0.61± 0.08 c 0.618±0.31c 0.598± 0.10c
O. gratissimum 50 0.532±0.13a 0.498± 0.47c 0.502±0.29c 0.49± 0.18 c 0.444± 0.19c
O. gratissimum 100 0.450± 0.68b 0.462±0.17 c 0.434±0.09 c 0.442± 0.20 c 0.414± 0.09c
O. gratissimum 200 0.556±0.07 a 0.452± 0.16c 0.386±0.24c 0.386± 0.24 c 0.400 0.374c
p<0.001 p<0.001 p<0.01 p<0.001 p<0.001
One way ANOVA F=4.502 F= 17.014 F= 30.798 F= 35.929 F= 89.528

Each value is mean ±SEM of 5 rats. ap<0.05; bp<0.01; cp<0.001 compared to control. NS: statistically not significant