Table 5.

Pharmacokinetic parameters of Norfloxacin alone and in combination with Piperine. (Values expressed as mcg/ml are Mean ± S.D.)^*

Treatment	Tmax	Cmax	t½	AUC
	(hr)	(mcg/ml)	(hr)	(mcg/ml/hr)
Norfloxacin (150mg/kg) po	3.1±0.32	11±0.26	1.75±0.38	63.976±0.51
Norfloxacin (150 mg/kg) + Piperine (20 mg/kg)po	3.2±0.31	16.1±0.27	2.97±0.38	111.695±0.54

^*p<0.05