Table 2.
Effect of aqueous leaves extract of Ageratum conyzoides (A.C) on blood glucose levels after oral administration in diabetics rats.
| Group (n=5) |
Dose | Blood glucose levels at different hours after the treatment(mg/dl) | ||||
| 0h | 1.5h | 3h | 5h | 8h | ||
|
Control (distilled water) |
10ml/kg | 372±14.53 | 342.02±24.11 (−8.06%) |
361±8.57 (−2.96%) |
362.40±9.86 (−2.58%) |
363.44±20.46 (−2.30%) |
| A. C | 100mg/kg | 365.7±8.30 | 350.05±6.24* (−4.28%) |
342.70±10.47 (−6.29%) |
300.9±67.93 (−17.72%) |
292.08±15.43* (−20.13%) |
| A. C | 200mg/kg | 370±13.55 | 348.73±11.19** (−5.75%) |
314.28±22.80** (−15.06%) |
312.43±34.93* (−15.56%) |
296±34.64** (−20%) |
| A. C | 300mg/kg | 380±40.60 | 314.11±54.15* (−17.34%) |
310.23±24* (−18.36%) |
314.30±17.39* (−17.29%) |
276.83±22.19** (−27.15%) |
| Glibenclamide | 10mg/kg | 369.2±30 | 342.84±34.38* (−7.14%) |
369.2±20.06 (0%) |
357.13±35.32 (−3.27%) |
312.05±29.44** (−15.48%) |
The values in brackets represent the percentage reduction in blood glucose vs. initial value.
Values are means blood glucose levels ± S.E.M. of five animals.
*
p<0.1
**
p<0.01 compared with the initial level of blood glucose of the rats (0h) in the respective group.