Table 2.
Effect of ME on Response Times in the Hot-Plate Test
| Treatment groups |
Doses mg/kg |
Mean response latencies ± SEM | ||||
| 0 | 30 | 60 | 90 | 120 | ||
| Control | - | 5.33 ± 1.03 | 5.17 ± 0.75 | 5.33 ± 2.07 | 5.5 ± 2.35 | 5.5 ± 2.35 |
| Morphine | 20 | 6.33 ± 1.91 | 34.33 ± 4.13* | 30.5 ± 4.46* | 16.17 ± 2.04* | 10.5 ± 0.84* |
| ME | 250 | 6.0 ± 1.26 | 9.17 ± 2.79* | 14.33 ± 2.5* | 22.67 ± 8.04* | 12.17 ± 3.87* |
| ME | 500 | 5.67 ± 1.21 | 8.83 ± 1.6* | 17.5 ± 4.37* | 28.83 ± 8.73* | 17.17 ± 7.63* |
| ME | 1000 | 6.33 ± 1.21 | 19.5 ±2.74* | 24.1 ± 4.05* | 30.5± 3.83* | 21.33 ± 5.35* |