Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Incorporation of DOR into the autophagy pathway. The autophagy pathway is explained in detail in the main text. Upon cellular stress, DOR is exported from the nucleus and possibly aids the beclin 1/Vps34 complex in the nucleation of the autophagosome. LC3 and GATE16 localize to the autophagsome during its formation and form a complex with DOR. DOR is detached from the autophagsome before it becomes an autolysosome, in which the targeted cellular components are degraded.
