Table 2. Concordances between the three CTC detection techniques.
K coefficient | P-value | Degree of agreement | Agreement (%) | |
---|---|---|---|---|
Comparison with the CellSearch CTC test | ||||
AdnaTest | 0.543 | <0.001 | Moderate | 81 |
RT–PCR for CK-19 | 0.356 | 0.002 | Fair | 72 |
RT–PCR for mammaglobin | 0.220 | 0.04 | Fair | 60 |
RT–PCR for CK-19 and/or mammaglobin | 0.203 | 0.04 | Fair | 57 |
Comparison with the AdnaTest | ||||
RT–PCR for CK-19 | 0.415 | <0.001 | Moderate | 78 |
RT–PCR for mammaglobin | 0.082 | 0.37 | Slight | 53 |
RT–PCR for CK-19 and/or mammaglobin | 0.109 | 0.189 | Slight | 50 |
Abbreviations: CTC=circulating tumour cell; ER=oestrogen receptor; PR=progesterone receptor; RT–PCR=reverse transcription–PCR.