Table 4. Comparison of positivity rates for CTC detection in MBC.
Reference | Method | Volume (ml) | No. of patients | No. of samples | Positivity rate (% of samples) |
---|---|---|---|---|---|
Allard et al (2004) | CellSearch | 7.5 | 422 | 1316 | 37a |
Cristofanilli et al (2004) | CellSearch | 7.5 | 177 | NA | 61a |
Zieglschmid et al (2007a) | AdnaGen | 2 × 5 | 48 | NA | 69 |
Aktas et al (2009) | AdnaGen | 2 × 5 | 39 | 226 | 31 |
Abbreviation: NA=not applicable.
Positivity rate defined as 2 or more CTC per 7.5 ml peripheral blood.