Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2009 Dec 15;102(2):361–368. doi: 10.1038/sj.bjc.6605478

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2010 Cancer Research UK

This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

(A) Schematic view of PSMB7 gene with its eight exons. Splitting positions of tested siRNA oligos are shown (↓); the most effective siRNA is marked by continuously bordered box. Binding location of designed PCR primers specific for PSMB7 is shown under the gene by a broken line (↓). Positions of probe sequences of probeset 200786_at on Affymetrix HG-U133A array are also shown (▴, match probes; ▵, junction probes, overlapping two neighbouring exons). (B) Details of designed siRNA oligos. One out of three siRNA oligos (degrading at 548 nucleotide (nt)) showed effective silencing compared with siRNA-untreated control. GAPDH was used as internal control for both untreated control and siRNA-treated samples. The effect of silencing was 87% for siRNA binding at position 548.