Skip to main content
. 2009 Dec 8;102(2):414–418. doi: 10.1038/sj.bjc.6605485

Table 2. (a) Common SNPs with significant difference in the frequency of alleles in 192 familial cases and 192 controls and (b) Haplotype analysis of the three common SNPs in the promoter region in 192 familial cases and 192 controls.

(a)
SNP NCBI 36 coordinates SNP ID Associated allele Frequency in cases Frequency in controls P-value
SNP2 10: 51218461 ENSSNP10237085 C 0.094 0.048 0.0172
             
SNP8 10: 51219320 rs12770171 T 0.236 0.151 0.0036
             
SNP9 10: 51219502 rs10993994 T 0.453 0.352 0.0052
             
(b)
Haplotype Frequency Case, control ratio counts Case, control frequencies χ 2 P-value  
SNP 2,8 and 9            
TCC 0.597 210.5 : 173.5, 234.6 : 127.4 0.548, 0.648 7.721 0.0055  
TCT 0.209 83.2 : 300.8, 72.9 : 289.1 0.217, 0.201 0.259 0.6111  
TTT 0.122 54.4 : 329.6, 36.4 : 325.6 0.142, 0.101 2.934 0.0868  
CTT 0.073 36.0 : 348.0, 18.1 : 343.9 0.094, 0.050 5.287 0.0215