Table 3. Haplotype analysis of SNP 8 rs1277017 and SNP 9 rs10,993,994 using our data from stage1 and 2 genome-wide association study (GWAS) adjusted for strata (Eeles et al, 2008).
|
Haplotype
|
|||||
|---|---|---|---|---|---|
| Na | rs10993994 | rs1277017 | P-value | Freqb | Odds ratioc (OR) |
| 1 | 1 C | 1 C | 0.580 | 1 | |
| 2 | 1 C | 2 T | 0.35 | 0.0021 | 1.38 (0.71–2.04) |
| 3 | 2 T | 1 C | 7.0 × 10−18 | 0.210 | 1.35 (1.28–1.42) |
| 4 | 2 T | 2 T | 3.7 × 10−19 | 0.208 | 1.37 (1.30–1.44) |
a
Haplotype number.
b
Haplotype frequencies.
c
Odds ratio and 95% confidence interval.