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. 2010 Feb 5;6(2):e1000752. doi: 10.1371/journal.ppat.1000752

Figure 2. PK and PK-related mutant strains show a damage response in the absence of cell wall stress.

Figure 2

(A) The expression of six genes upregulated by caspofungin treatment, DDR48, SOD5, STP4, ALS1, RTA4, and ECM331, was analyzed in PK and PK-related mutant strains in the absence of cell well stress. The expression of TDH3, a gene involved in glycolysis, was used to normalize expression between strains and expression values were further normalized to wild type (DAY185) expression for comparison between experiments. Resultant values were log base 2 transformed (wild type expression for all six genes is therefore at 0). (B) A graphical representation of the expression data. Arrows point to targets upregulated in all (solid arrows), most (dashed lines), or half (dotted lines) of the mutants indicated in the clusters.