Table 1.
Clinical profile of patients with GCT with lung metastases in the metastasectomy group
| Patient | Age (years) | Gender | Location of primary | Treatment of primary lesion | Local recurrence/Interval | Interval to metastasis | Treatment of metastases |
|---|---|---|---|---|---|---|---|
| 1 | 32 | Male | Tibia, upper end | Wide excision | Nil | 11 years | Metastatectomy + chemotherapy |
| 2 | 25 | Male | Humerus, upper end | Wide excision | Nil | 1 year | Metastatectomy |
| 3 | 25 | Male | Tibia, upper end | Wide excision | Once at 15 months | 3 years | Metastatectomy |
| 4 | 16 | Male | Tibia, upper end | Wide excision | Nil | 5 months | Metastatectomy |
| 5 | 26 | Female | Femur, lower end | Amputation | Once at 10 months | 12 months* | Metastatectomy |
| 6 | 21 | Female | Femur, lower end | Wide excision | Nil | At presentation* | Metastatectomy |
| 7 | 26 | Male | Pelvis | Hemipelvectomy | Nil | 6 months* | Metastatectomy |
| 8 | 20 | Female | Forefinger | Amputation | Nil | 2 yrs | Metastatectomy + chemotherapy |
* Patients 5, 6, and 7 had metastasis to the inguinal lymph node, scalp, and calf muscle; GCT = giant cell tumor. (Reprinted with permission from Gupta R, Seethalakshmi V, Jambhekar NA, Prabhudesai S, Merchant N, Puri A, Agarwal M. Clinicopathologic profile of 470 giant cell tumors of bone from a cancer hospital in western India. Ann Diagn Pathol. 2008;12:239–248.)