Table 5.
Previously reported retinal gene expression changes in the rat STZ model at 3 months diabetes examined in the STZ mouse and Ins2Akita mouse models by quantitative polymerase chain reaction
| Gene | Model | ||
|---|---|---|---|
| Rat STZa | Ins2Akita | Mouse STZ | |
| C1INH (Serping1) | 2.6** | 1.8* | 2.1* |
| C1S | 2.8** | – | – |
| Carhsp1 | 2.6*** | – | – |
| Ccr5 | 1.6** | – | – |
| Chi3L1 | 2.7** | – | – |
| Dcamkl1 | 0.8** | – | – |
| Edn2 | 3.7* | – | – |
| Ednrb | 1.6** | – | – |
| Slc6a11 (Gat3) | 0.6*** | – | – |
| Gbp2 | 2.4* | – | 2.8*** |
| Hspb1 | 14.2** | – | – |
| Icam1 | 1.7** | – | – |
| Jak3 | 1.9** | – | – |
| Kcne2 | 0.5*** | 0.8 ** | 0.8* |
| Lama5 | 1.8*** | 1.4 ** | – |
| Lgals3 | 8.0*** | – | – |
| Lgals3bp | 1.7* | – | 2.0* |
| Mct1 | 0.6*** | – | – |
| Nppa | 0.5*** | – | – |
| Pcgf1 | 0.7*** | – | – |
| Pedf | 1.9* | – | – |
| Stat3 | 1.4** | – | – |
| Timp1 | 4.0** | – | – |
| Tnfrsf12a | 2.2*** | – | – |
– not changed
*p < 0.05 (t test)
**p < 0.01 (t test)
***p < 0.001 (t test)
aPrimary quantitative polymerase chain reaction data for STZ rats was previously reported [4]