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. 2004 Jun 30;19(3):374–383. doi: 10.3346/jkms.2004.19.3.374

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Copyright © 2004 The Korean Academy of Medical Sciences

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 1 — Photograph of stained 6% denaturing polyacrylamide gel showing relative mobilities of linear and circular antisense TGF-β1 oligodeoxynucleotides (ODNs). (A) Synthesis of circular antisense TGF-β1 ODNs from linear ODNs: lane 1, 58-nt linear antisense TGF-β1 ODNs; lane 2, 116-nt circular antisense TGF-β1 ODNs. (B) Stability of circular and linear antisense TGF-β1 ODNs after the treatment with rat serum: lane 1, untreated circular antisense TGF-β1 ODNs; lane 2, circular antisense TGF-β1 ODNs treated with 50% (v/v) rat serum for 24 hr; lane 3, untreated linear antisense TGF-β1 ODNs; lane 4, linear antisense TGF-β1 ODNs treated with 50% (v/v) rat serum for 24 hr.