Fig. 1.

This schematic illustration shows the probe layout for the 17 mer oligonucleotide sequences noted in Table 1 and the interpretative results of oligonucleotide chips for YMDD motif mutation detection. The oligonucleotide probes are patterned as duplex arrays. ① Positive is mixture of HB552-WM, HB552-MV, HB552-MI1, HB552-MI2 and HB552-MI3 probes (Table 1), ② 522WM, ③ 552MI3, ④ 552MI2, ⑤ 552MI1 and ⑥ 552MV indicates HB552-WM, HB552-MV, HB552-MI1, HB552-MI2 and HB552-MI3 probes, respectively.