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Time constant values for return of deoxyhemoglobin concentration toward baseline values: recovery time curves are fitted by using an exponential model and shown as mean±standard deviation. Analysis was performed using ANOVA assuming unequal variances; in comparing cobinamide to controls, p<0.0001 for the deoxyhemoglobin time constant.
| Time constant\group | Control | Hydroxocobalamin | Cobinamide |
|---|---|---|---|
| Deoxyhemoglobin recovery (min) | 76.4±42.7 | 75.4±25.1 | 13.8±7.1 |
