Figure 1.

Follicular lymphoma grade 3a involving the tonsil (A) with a simultanous DLBCL component in deeper parts of the tumor (B) with higher magnification in the inserts, (A+B Giemsa stain). Strong expression of BCL2 (C) in the absence of BCL2 breaks (insert in C) and dense networks of follicular dendritic cells positive for CD23 (D), A-D correspond to case 5 in Tables 1 and 2). A floral follicular growth pattern in case 12 highlighted by staining for CD10 (E). Breaks in the IGH gene of case 13 (F, arrows indicate the split signal).