Figure 2.
Effect of ITF2357 on genes involved in cell-cycling, apoptosis and immunity. The average fold change in expression level of treated versus untreated control at 2 and 6 h is shown for each gene. Genes related to cell cycling (A), apoptosis (B) and immunity/inflammation (C) are ranked according to their fold change at 6 h of treatment. The probe set with the highest zg score was selected whenever more than one recognized the same gene.* indicates genes that were also significantly modulated at 2 h. +in panel C indicates genes specifically modulated at 2 h.