Table 7.
Cardiovascular risk factors and current methotrexate (MTX) use
| Factor | MTX (N = 9) | No MTX (N = 90) | P | P(Adjusted) |
|---|---|---|---|---|
| Systolic BP (mm Hg) | 133.4 ± 19.9 | 118.2 ± 17.0 | 0.01 | 0.047 |
| Diastolic BP (mm Hg) | 79.7 ± 16.1 | 73.2 ± 13.5 | 0.16 | 0.33 |
| HDL cholesterol (mg/dL) | 43.2 ± 13.9 | 48.4 ± 14.8 | 0.28 | 0.46 |
| LDL cholesterol (mg/dL) | 123.2 ± 28.2 | 103.6 ± 37.8 | 0.06 | 0.23 |
| Triglycerides (mg/dL) | 161.7 ± 56.2 | 115.2 ± 58.3 | 0.02 | 0.05 |
| Glucose (mg/dL) | 88.1 ± 12.5 | 87.0 ± 28.1 | 0.25 | 0.96 |
| Homocysteine(umol/L) | 11.22 ± 3.07 | 9.09 ± 2.69 | 0.03 | 0.08 |
| F2 Isoprostane (ng/mg Creatinine) | 3.11 ± 3.30 | 2.80 ± 2.24 | 0.87 | 0.85 |
P = unadjusted P values; P (adjusted) = adjusted for age, sex, and SLEDAI. Data are shown as mean ± SD.