Fig. 2.

CXCR3 and CD3 activation have synergistic effects on T cell proliferation. A range of OKT3 concentrations were bound to a 96-well plate overnight. 10 nM CXCL10 was also bound to the plate overnight (-▾-), added in solution to the lymphocyte suspension (-▴-), or controlled with PBS (-■-). The assay was incubated for 72 h and T cell proliferation was determined by measuring ³H-thymidine incorporation. Representative results are shown from one of three similar assays; the bars show mean values ± SEM.