Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2009 Nov 24;38(3):797–809. doi: 10.1093/nar/gkp1072

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2009. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5/uk/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 6. — Effect of HIF-1α downregulation on repair kinetics of 6-4PPs and CPDs. Keratinocytes were harvested at different times after UVB-irradiation and levels of 6-4PPs and CPD were analyzed by flow cytometry following fluorescent immunostaining with the corresponding specific antibody. (A) Representative histogram illustrating the 6-4PPs level at different time points after irradiation in non-transduced or shHIF-1α-transduced keratinocytes. (B) The percentage of 6-4PPs remaining at various time points after irradiation was evaluated by comparison with the initial levels. The results are expressed as the mean ± SD of three independent experiments. (C) Representative histogram illustrating levels of CPDs at different time points after irradiation. (D) The percentage of CPDs remaining at different time points after irradiation was evaluated and the results are expressed as the mean ± SD of three independent experiments. *P < 0.05 for shHIF-1α-transduced cells at the indicated time points versus corresponding non-transduced cells.