Table 1.
Influence of DNA base sequence on the BII percentages in free DNA in solution
| N | %BII | TRX score | |
|---|---|---|---|
| CpG•CpG | 25 | 43•43 | 43 |
| CpA•TpG | 28 | 52•31 | 42 |
| GpG•CpC | 11 | 47•37 | 42 |
| GpC•GpC | 22 | 25•25 | 25 |
| GpA•TpC | 25 | 33•11 | 22 |
| TpA•TpA | 12 | 14•14 | 14 |
| ApG•CpT | 19 | 18•0 | 9 |
| ApA•TpT | 17 | 11•0 | 5 |
| ApC•GpT | 23 | 8•0 | 4 |
| ApT•ApT | 22 | 0•0 | 0 |
The DNA sequence is expressed in terms of the 10 complementary dinucleotides, of frequency N in the NMR data collected from the literature. The BII percentages (%BII) are given for each partner in a complementary dinucleotide. The average standard deviation of %BII is ±8. The TRX scores are the half-sums of the %BII observed for two facing phosphates in a complementary dinucleotide. The %BII and TRX scores higher (in bold) and lower than average (which is 21) correspond to enhanced and restricted flexibilities, respectively. A maximal flexibility on this scale corresponds to a TRX score of 50.