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Inflammatory response (TNF-α secretion) of CD patient's PBMCs in presence of somatostatin analogs. CD patients PBMCs (5 · 105 cells/mL) were activated by LPS for 24 hours in presence of increasing doses of somatostatin analogs (10−7 M to 10−5 M). Quantitative evaluation of the secreted cytokine TNF-α was done by sandwich ELISA as described in Materials and Methods.
