Fig. 2.

Effect of licorice compounds on MPP⁺-induced activation of caspase-3. PC12 cells were treated with 500µM MPP⁺ in the presence of licorice compounds (10~50µM) or scavengers [1 mM N-acetylcysteine (NAC), 30µM trolox or 30 µM carboxy-PTIO (PTIO)] for 24 h. Data are expressed as units for caspase-3 activity and represent means ± SEM (n=6). ⁺p<0.05 compared to control; and ^*p<0.05 compared to MPP⁺ alone.