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Gene map and linkage disequilibrium (LD) in matrix metallopeptidase 2 (MMP2) gene. (A) Gene map of single nucleotide polymorphisms (SNPs) in MMP2 on chromosome 16. Exons are marked with box. The coding region is black-boxed and untranslation regions are white-boxed. Asterisk (*) indicates a significant SNP. Arrow indicates the location of each SNP. EX, exon. (B) LD coefficient (|D'|) and LD blocks among SNPs of MMP2. Block 1 consists of rs17242319, rs1053605, rs243849, and rs2287074.
