TABLE 2.
Analysis of left ventricular function in young and aged SHHF and FBN rats
| Group | LVIDd (mm) | LVIDs (mm) | FS (%) | EF (%) | AWTd (mm) | PWTd (mm) | |
|---|---|---|---|---|---|---|---|
| SHHF | Non-HF | 6.4 ± 0.1 | 3.9 ± 0.2 | 39 ± 2 | 77 ± 2 | 1.4 ± 0.1# | 1.4 ± 0.1 |
| HF | 8.0 ± 0.2 | 6.1 ± 0.2 | 24 ± 2 | 56 ± 3 | 1.9 ± 0.1* | 1.8 ± 0.1* | |
| FBN | Young | 5.3 ± 0.1 | 2.5 ± 0.3 | 54 ± 3 | 89 ± 3 | 1.5 ± 0.04 | 1.5 ± 0.06 |
| Aged | 6.3 ± 0.2 | 2.9 ± 0.2 | 54 ± 3 | 89 ± 2 | 1.6 ± 0.1 | 1.7 ± 0.06* |
Data for various markers of LV morphology and function are presented as mean ± SE (n = 8 per group SHHF, n = 4–6 per group FBN). LVIDd, left ventricular internal diameter in diastole; LVIDs, left ventricular internal diameter in systole; FS, fractional shortening; EF, ejection fraction; AWTd, left ventricular anterior wall thickness in diastole; PWTd, left ventricular posterior wall thickness in diastole. *P < 0.05 versus SHHF nonHF; #P < 0.05 versus SHHF HF; †P < 0.05 versus FBN young; ‡P < 0.05 versus FBN aged within same column.